San Francisco 49ers running back Christian McCaffrey suffered a knee injury during Sunday night’s game against the Buffalo Bills, leading to an early exit. McCaffrey, who had been dealing with previous injuries this season, slid on a run without contact, prompting immediate concern. He got up quickly and jogged to the sideline before visiting the medical tent and then heading to the locker room. He was ruled out for the rest of the game.
This injury is a major blow for the 49ers, who have already faced numerous injury setbacks this season. McCaffrey, after missing the first eight games due to Achilles and calf issues, had struggled to return to his usual form. Despite a promising 19-yard gain on Sunday night, he had accumulated only 53 yards on seven carries before the injury.
McCaffrey’s previous calf issue had already kept him out of preseason and training camp, and this latest injury raises significant concerns for his ability to finish the season strong. His health will be a key factor for the 49ers moving forward, especially as they face mounting injuries throughout their roster.